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What is emphysema? Understanding causes, symptoms, and treatment options

Emphysema is a chronic and progressive lung disease that damages the air sacs in the lungs, making it difficult to breathe. This article breaks down what emphysema is, its causes, symptoms, treatment strategies, and what to expect as the disease progresses.
4 minutes
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May 6 2025
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Medical
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Lung cancer
Alessia Casali

Emphysema is a type of chronic obstructive pulmonary disease (COPD) that causes permanent damage to the alveoli — the tiny air sacs in the lungs where oxygen is exchanged with the blood. When these air sacs are destroyed, the lungs lose their elasticity and ability to fully exhale, trapping stale air inside and making it difficult to breathe.

Over time, emphysema reduces the surface area for gas exchange, resulting in low oxygen levels in the blood and shortness of breath, especially during exertion.

What causes emphysema?

The most common cause of emphysema is long-term exposure to airborne irritants, especially:

  • Cigarette smoke (responsible for the vast majority of cases)
  • Secondhand smoke
  • Air pollution
  • Chemical fumes and industrial dust

A small percentage of cases are caused by a rare inherited condition called alpha-1 antitrypsin deficiency, in which the body lacks a protein that protects lung tissue from damage. People with this condition can develop emphysema even if they’ve never smoked.

Symptoms of emphysema

Emphysema develops gradually, and symptoms may not be noticeable until the lungs have already suffered significant damage. Common signs include:

  • Shortness of breath — especially during physical activity
  • Chronic cough — often with mucus
  • Wheezing or chest tightness
  • Fatigue or reduced exercise tolerance
  • Weight loss in advanced stages
  • Barrel-shaped chest (due to overinflation of the lungs)

As the disease progresses, even basic activities like walking, eating, or talking may cause breathlessness.

Diagnosing emphysema

To diagnose emphysema, your doctor may use a combination of:

  • Spirometry (lung function test) – Measures how much air you can exhale and how fast
  • Chest X-ray or CT scan – Helps visualize lung damage
  • Arterial blood gas test – Evaluates oxygen and carbon dioxide levels in the blood
  • Alpha-1 antitrypsin test – Screens for genetic causes, especially in younger or non-smoking patients

Early diagnosis is important to slow disease progression and improve outcomes.

Is emphysema curable?

Unfortunately, emphysema cannot be cured. The damage to the lungs is permanent. However, many treatments can help manage symptoms, prevent complications, and improve quality of life. The earlier the condition is detected, the more options are available for effective management.

Treatment options

The goal of emphysema treatment is to ease breathing, reduce symptoms, and slow progression.

1. Quitting smoking

The single most important step. Smoking cessation prevents further lung damage and enhances the effectiveness of other treatments.

2. Medications

  • Bronchodilators (inhalers) to open airways
  • Steroids to reduce inflammation
  • Antibiotics for respiratory infections
  • Mucolytics to thin mucus

3. Pulmonary rehabilitation

A medically supervised program that combines exercise training, education, and support. It improves stamina and teaches breathing techniques.

4. Oxygen therapy

For patients with low blood oxygen levels, supplemental oxygen can reduce symptoms, improve sleep, and increase energy levels.

5. Surgical options

  • Lung volume reduction surgery (LVRS) – Removes damaged lung tissue to improve breathing
  • Lung transplant – An option for end-stage patients under strict eligibility criteria

Lifestyle adjustments and home care

Living with emphysema requires adapting daily habits to manage symptoms and avoid flare-ups. Some helpful strategies include:

  • Using air purifiers to reduce indoor pollutants
  • Avoiding cold air, dust, and smoke
  • Eating a healthy, high-protein diet
  • Pacing yourself during daily tasks
  • Staying hydrated to loosen mucus
  • Getting flu and pneumonia vaccines annually

Support from family, caregivers, and healthcare teams is vital in creating a stable, safe environment.

Emotional well-being and emphysema

Chronic diseases like emphysema can take a toll not just physically but emotionally. Many patients experience anxiety, depression, or social isolation due to breathing limitations or fear of exacerbations.

Mental health support, including therapy, mindfulness, and support groups, can improve quality of life and help patients cope with the emotional burden of the disease.

Planning for the future

For individuals with advanced emphysema and limited treatment options, it can be empowering to think about long-term planning. This may include:

  • Advanced care directives
  • Palliative care discussions
  • Exploring emerging medical technologies

A future-facing option: cryopreservation

When treatment reaches its limits, some patients choose to look beyond what today’s medicine can offer. At Tomorrow.bio, we provide human cryopreservation — the preservation of individuals at ultra-low temperatures after legal death, with the goal of future revival when medicine has progressed.

Cryopreservation is not a cure or a promise. It is, however, a choice to preserve possibility — to hold open the door to a time when emphysema and other terminal conditions may be treatable.

We’re here to guide anyone considering this option, with honesty, care, and respect.

About Tomorrow.bio

At Tomorrow.bio, we are dedicated to advancing the science of cryopreservation with the goal of giving people a second chance at life. As Europe’s leading human cryopreservation provider, we focus on rapid, high-quality standby, stabilization, and storage of terminal patients — preserving them until future medical technologies may allow revival and treatment.

Our mission is to make human cryopreservation a reliable and accessible option for everyone. We believe that no life should end because current medical capabilities fall short.

Our vision is a future where death is optional — where people have the freedom to choose long-term preservation in the face of terminal illness or fatal injury, and to awaken when medicine has caught up.

📧 Contact us at: hello@tomorrow.bio
🌐 Visit our website: www.tomorrow.bio
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