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What is human cryopreservation? The science behind pausing death

Human cryopreservation is the process of preserving the body and brain after legal death at extremely low temperatures in hopes of future revival. This article explores how it works, what makes it scientifically valid, and why more people are turning to this forward-looking end-of-life choice.
4 minutes
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May 6 2025
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Cryonics
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Cryopreservation
Alessia Casali

What is human cryopreservation?

Human cryopreservation is the medical process of preserving a legally dead individual at ultra-low temperatures — usually around -196°C — using a method that avoids ice formation and protects tissues from decay.

The goal? To keep the body and brain intact so that, if medical technology advances far enough, the person may one day be revived and treated.

Cryopreservation is based on real science — not freezing people like in science fiction, but using vitrification, a technique that transforms body fluids into a stable, glass-like state without damaging ice crystals.

Cryopreservation vs. freezing

Traditional freezing leads to ice formation. Ice crystals expand and destroy cells, especially delicate brain tissue.

Cryopreservation uses vitrification, which:

  • Replaces bodily fluids with cryoprotective agents
  • Rapidly cools the body to avoid crystal formation
  • Solidifies tissues in a non-crystalline state, preserving structure and chemistry

This difference is crucial — and it's why real-world cryonics relies on vitrification, not conventional freezing.

How does human cryopreservation work?

At Tomorrow.bio, human cryopreservation involves several precise steps:

  1. Standby and monitoring
    A medical team is on standby as the patient approaches legal death.
  2. Stabilization after death
    As soon as death is declared, the team begins cooling the body and administering medications to slow biological degradation.
  3. Cryoprotective perfusion
    Blood is replaced with cryoprotectants to prevent ice formation.
  4. Gradual cooling to -196°C
    The body is cooled in stages and stored in liquid nitrogen for the long term.
  5. Monitoring and maintenance
    The preserved patient is stored in a specialized dewar — not requiring electricity, just periodic liquid nitrogen replenishment.

This protocol aims to preserve the brain’s fine structure, which may encode memory, personality, and identity.

When does cryopreservation happen?

Cryopreservation can only legally begin after death has been declared — typically by a physician or medical authority.

This makes response time critical. The sooner the body is stabilized and cooled, the better the preservation quality. Tomorrow.bio provides 24/7 standby teams in supported regions to minimize delays.

Is revival possible?

Currently, no human has been revived after cryopreservation. Revival technology — including nanomedicine, organ regeneration, and neurorepair — does not yet exist.

However, preservation is possible today, and it's getting better. The goal is to keep the body and brain intact so that, if and when those future medical capabilities arrive, revival will not be ruled out by poor preservation.

Think of cryopreservation as rescue through time — a way to stay eligible for future treatment.

Who chooses cryopreservation?

People from all walks of life sign up, including:

  • Scientists and futurists
  • Terminally ill patients
  • Bioethics advocates
  • Families who’ve lost someone suddenly
  • Longevity enthusiasts planning for what’s next

They don’t believe they’re guaranteed to come back. They believe that preserving the option is better than losing it altogether.

What about pets?

Human cryopreservation isn’t the only option anymore. Tomorrow.bio also offers pet cryopreservation, using similar protocols to preserve beloved animal companions.

You can calculate your pet’s preservation cost with our calculator.

Why human cryopreservation matters

Medicine is advancing rapidly — but it still fails millions of people every year. Cryopreservation doesn’t fix that. But it says:

  • “Don’t discard what we may one day repair.”
  • “Don’t accept that current limitations are the final word.”
  • “Give the future a chance to help.”

If you believe in progress, in dignity at the end of life, and in the value of second chances, cryopreservation might make sense for you.

About Tomorrow.bio

At Tomorrow.bio, we are dedicated to advancing the science of cryopreservation with the goal of giving people and pets a second chance at life. As Europe’s leading cryopreservation provider, we focus on rapid, high-quality standby, stabilization, and storage of terminal patients — preserving them until future medical technologies may allow revival and treatment.

Our mission is to make cryopreservation a reliable and accessible option for everyone. We believe that no life — human or animal — should end because current medical capabilities fall short.

📧 Contact us at: hello@tomorrow.bio
🌐 Visit our website: www.tomorrow.bio
🤝 Schedule a consultation: Book a call